Antibiotics are important in controlling bacterial overgrowth in the intestines as well as treating infections such as abscesses. They are useful for treating active Crohn's disease and pouchitis in ulcerative colitis patients who have undergone an ileoanal-pouch procedure.
Typical antibiotics are ciprofloxacin (Cipro) and metronidazole (Flagyl). Either antibiotic, used alone or in combination, is effective and can help maintain remission. Because patients may be on long-term therapy, antibiotics carry a risk of side effects and many drug interactions.
Side Effects of Metronidazole (Flagyl)
taste disturbances
numbness and tingling of hands and feet
nausea
decreased appetite
flushing and malaise with the use of alcohol
Side Effects of Ciprofloxacin (Cipro)
nausea
susceptibility to the sun: increased risk of sunburn, skin reaction
decreased absorption with calcium and iron supplements, antacids
